20
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T8883 | Pizuglanstat | Others , Prostaglandin Receptor | |
Pizuglanstat is a hematopoietic prostaglandin synthase inhibitor. | |||
T5014 | Prostaglandin E2 | PGE2,Dinoprostone,Prostaglandin E2 (PGE2) | Endogenous Metabolite , Prostaglandin Receptor |
Prostaglandin E2 (PGE2) is a naturally occurring hormone involved in a variety of physiological processes in the body, including smooth muscle contraction and relaxation, regulation of vasodilatation and constriction, re... | |||
T15133 | Dinoprost | Prostaglandin F2a,PGF2α | Endogenous Metabolite |
Dinoprost (Prostaglandin F2a) is a naturally occurring prostaglandin. It is used in medicine to induce labor and as an abortifacient. | |||
T9153 | Picotamide | Others | |
Picotamide has anticoagulant and fibrinolytic properties. | |||
T15681 | L-161982 | Prostaglandin Receptor | |
L-161982 is a selective antagonist of EP4 receptor. L-161982 could inhibit PGE2-induced ERK phosphorylation and cell proliferation of HCA-7 cells. L-161982 could alleviate collagen-induced arthritis in mice. | |||
T5505 | Terutroban | Prostaglandin Receptor | |
Terutroban, a thromboxane prostaglandin receptor antagonist, affects the progression of atherosclerosis. | |||
T5386 | Asapiprant | Prostaglandin Receptor | |
Asapiprant (S-555739) is a potent and selective DP1 receptor antagonist (Ki: 0.44 nM). It exhibited high affinity and selectivity for the DP1 receptor. | |||
T1626 | Prostaglandin E1 | PGE1,Alprostadil | Endogenous Metabolite , Prostaglandin Receptor |
Prostaglandin E1 (Alprostadil) is the naturally occurring prostaglandin E1 (PGE1) which displays a variety of pharmacologic actions. Prostaglandin E1 is a potent vasodilator agent that increases peripheral blood flow, in... | |||
T11211 | EP4 receptor antagonist 1 | Prostaglandin Receptor | |
EP4 Receptor Antagonist 1 is a highly potent and selective competitive prostanoid EP4 receptor antagonist, effective for cancer immunotherapy. It inhibits both human and mouse EP4 receptors with IC50 values of 6.1 nM and... | |||
T2428 | TG6-10-1 | 5-HT Receptor , Prostaglandin Receptor | |
TG6-10-1 is an EP2 antagonist. | |||
T5482 | TG4-155 | Prostaglandin Receptor | |
TG4-155 is a brain penetrant EP2 antagonist (KB = 2.4 nM) that is over 1000-fold less effective at EP4 (KB = 11.4 µM) and a panel of other receptors and channels | |||
T14148 | AH 6809 | Prostaglandin Receptor | |
AH 6809 is an antagonist of EP and DP receptor(with Kis of 1217, 1150, 1597, and 1415 nM for the cloned human EP1, EP2, EP3-III, and DP receptor respectively). AH 6809 has a Ki of 350 nM for mouse EP2 receptor. | |||
T2S0765 | Epibetulinic acid | NO Synthase , Prostaglandin Receptor | |
Epibetulinic acid has anti-inflammatory activity, it exhibits potent inhibitory effects on NO and prostaglandin E(2) production in mouse macrophages (RAW 264.7) stimulated with bacterial endotoxin. | |||
TQ0025 | E7046 | Prostaglandin Receptor | |
E7046 is a specific, orally bioavailable EP4 antagonist (IC50: 13.5 nM, Ki: 23.14 nM), exhibiting anti-tumor activities. | |||
T6399 | AZD1981 | GPR , Prostaglandin Receptor | |
AZD1981 is an effective and specific CRTh2 (DP2) receptor antagonist (IC50: 4 nM), showing >1000-fold selectivity over more than 340 other enzymes and receptors, including DP1. AZD1981 has been used in trials studying th... | |||
T4546 | Dinoprost tromethamine salt | Dinoprost Tromethamine,Zinoprost,Prostin F2 alpha,PGF2α THAM,Dinolytic,Prostaglandin F2α THAM | Apoptosis , Endogenous Metabolite , Prostaglandin Receptor , Autophagy , PROTAC Linker |
Dinoprost tromethamine salt (PGF2α THAM) is a naturally occurring prostaglandin used in medicine to induce labor and as an abortifacient. | |||
T16280 | Nedocromil | FPL 59002 | Leukotriene Receptor , Prostaglandin Receptor , Histamine Receptor |
Nedocromil (FPL 59002) inhibits the action or formation of multiple mediators. Which including histamine, leukotriene C4 (LTC4), and prostaglandin D2 (PGD2). | |||
T15712 | Laropiprant | MK-0524 | Prostaglandin Receptor |
Laropiprant (MK-0524) is a potent and selective antagonist of prostaglandin D2 (PGD2) receptor (DP) such as and DP/DP1 receptor(Ki = 0.57 nM) and TP Receptor(Ki = 2.95 nM). | |||
T14865 | Carboprost tromethamine | Prostaglandin Receptor | |
Carboprost tromethamine, a synthetic 15-methyl analogue of prostaglandin F2α, effectively promotes uterine contractions and significantly reduces bleeding during and post-delivery. | |||
T2664 | Timapiprant | OC000459 | GPR , Prostaglandin Receptor |
Timapiprant (OC000459) is a potent and selective D prostanoid receptor 2 (DP2) antagonist (IC50: 13 nM). |